Patient-specific modelling of pulmonary arterial hypertension: wall shear stress correlates with disease severity

Patient-specific modelling of pulmonary arterial hypertension: wall shear stress correlates with disease severity

IntroductionPulmonary arterial hypertension (PAH) requires an invasive right heart catheter (RHC) procedure for diagnosis. Patients can present with initial symptoms and interact with healthcare institutes for up to 3 years before referral for diagnosis. Thus, there is a great need to develop non-in...

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Main Authors: C. H. Armour, D. Gopalan, B. Statton, D. P. O’Regan, L. Howard, M. R. Wilkins, X. Y. Xu, A. Lawrie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
pulmonary arterial hypertension
computational fluid dynamics
4D-flow MRI
wall shear stress
non-invasive assessment
computational biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1585345/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1585345/full

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