Establishment of a novel mouse model of colorectal cancer by orthotopic transplantation

Abstract Background Colorectal cancer (CRC) represents a major malignancy that poses a significant threat to human health worldwide. The establishment of a reliable and pathologically relevant orthotopic model of CRC is crucial for gaining a deeper understanding of its molecular mechanisms and for d...

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Bibliographic Details
Main Authors: Cewen Chen, Qiaochu Fu, Lei Wang, Shinya Tanaka, Masamichi Imajo
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-13834-5
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