A genome-based survey of invasive pneumococci in Norway over four decades reveals lineage-specific responses to vaccination

Abstract Background Streptococcus pneumoniae is a major cause of mortality globally. The introduction of pneumococcal conjugate vaccines (PCVs) has reduced the incidence of the targeted serotypes significantly, but expansion of non-targeted serotypes, serotype replacement, and incomplete vaccine-tar...

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Bibliographic Details
Main Authors: Vegard Eldholm, Magnus N. Osnes, Martha L. Bjørnstad, Daniel Straume, Rebecca A. Gladstone
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Genome Medicine
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Online Access:https://doi.org/10.1186/s13073-024-01396-3
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