Patient-centered brain transcriptomic and multimodal imaging determinants of clinical progression, physical activity, and treatment needs in Parkinson’s disease

Abstract We continue to lack a clear understanding on how the biological and clinical complexity of Parkinson’s disease emerges from molecular to macroscopic brain interactions. Here, we use personalized multiscale spatiotemporal computational brain models to characterize for the first time the syne...

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Bibliographic Details
Main Authors: Quadri Adewale, Ahmed Faraz Khan, Sue-Jin Lin, Tobias R. Baumeister, Yashar Zeighami, Felix Carbonell, Daniel Ferreira, Yasser Iturria-Medina
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00878-4
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