Combined serine protease PRSS22 and CEA mRNA analysis identifies the majority of colon cancer patients that recur within 12 years

Combined serine protease PRSS22 and CEA mRNA analysis identifies the majority of colon cancer patients that recur within 12 years

IntroductionProteases play an important role in tumor progression. The predictive efficacy of proteases PRSS3 and PRSS22 mRNA levels for predicting relapse in surgically treated colon cancer (CC) patients was assessed.MethodsmRNA expression was quantified in 371 half lymph nodes (LNs) from 121 CC pa...

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Bibliographic Details
Main Authors: Alaa Mohamed, Manar AbdelMageed, Faten Zahran, Nabila Zein, Lina Olsson, Gudrun Lindmark, Marie-Louise Hammarström, Sten Hammarström, Basel Sitohy
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
colon cancer
serine proteases
PRSS3
PRSS22
CEA
regional lymph nodes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1628069/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1628069/full

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