First-in-class intranasal epinephrine spray for anaphylaxis: Dose finding clinical study

First-in-class intranasal epinephrine spray for anaphylaxis: Dose finding clinical study

Background: Anaphylaxis is a life-threatening clinical presentation of acute systemic allergic reactions. Timely administration of epinephrine, usually by intramuscular autoinjector, is a robust life-saving treatment. Despite the critical necessity, there are multiple deterrents to patients’ proper...

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Bibliographic Details
Main Authors: Tair Lapidot, PhD, Yuval Tal, MD, PhD, Dalia Megiddo, MD, Galia Temtsin Krayz, PhD, Carolina Abrutzky, BSc, Simcha Blotnick, PhD, Oded Shamriz, MD, Alon Hershko, MD, PhD, Yoseph Caraco, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Anaphylaxis
allergy
intranasal
bioavailability
epinephrine
powder
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000888
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