The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo.

<h4>Background</h4>In the 1950s, Reed and coworkers discovered an enzyme activity in Streptococcus faecalis (Enterococcus faecalis) extracts that inactivated the Escherichia. coli and E. faecalis pyruvate dehydrogenase complexes through cleavage of the lipoamide bond. The enzyme that cau...

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Bibliographic Details
Main Authors: Maroya D Spalding, Sean T Prigge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0007392&type=printable
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