Phosphorylation of GABAA receptor β3 subunit at Ser408–409 is essential for contextual learning at hippocampal CA1 synapses

Abstract Contextual learning requires strengthening at both AMPA receptor-mediated excitatory synapses and GABAA receptor-mediated inhibitory synapses in CA1 neurons. However, the precise mechanisms underlying learning-induced strengthening at inhibitory synapses have remained unclear. To address th...

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Bibliographic Details
Main Authors: Yuya Sakimoto, Yuheng Yang, Hiroyuki Kida, Dai Mitsushima
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-07637-8
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