Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux

Metabolism has been shown to alter cell fate in human pluripotent stem cells (hPSC). However, current understanding is almost exclusively based on work performed at 20% oxygen (air), with very few studies reporting on hPSC at physiological oxygen (5%). In this study, we integrated metabolic, transcr...

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Bibliographic Details
Main Authors: Jarmon G. Lees, Timothy S. Cliff, Amanda Gammilonghi, James G. Ryall, Stephen Dalton, David K. Gardner, Alexandra J. Harvey
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/8195614
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