Mitigation of polystyrene microplastic-induced hepatotoxicity in human hepatobiliary organoids through bile extraction

Mitigation of polystyrene microplastic-induced hepatotoxicity in human hepatobiliary organoids through bile extraction

Background & Aims: Polystyrene microplastics (PS-MPs) are pervasive in our daily life and can be ingested by the human body through bioaccumulation, causing organ damage, especially liver damage. However, the effect of PS-MPs bioaccumulation on human hepatotoxicity and their metabolism remai...

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Main Authors: Peilin Li, Daisuke Miyamoto, Tomohiko Adachi, Takanobu Hara, Akihiko Soyama, Hajime Matsushima, Hajime Imamura, Kengo Kanetaka, Weili Gu, Susumu Eguchi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Microplastic
Hepatotoxicity
Chemical induced progenitor cells
Organoid
bile metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014064
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