ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective

IntroductionIn mammals, the ubiquitin–proteasomal pathway plays a key role in the host antiviral response by targeting viral genes for degradation. Here, E1-activating enzymes, E2-conjugating enzymes, and E3 ligases attach the ubiquitin chain to molecules to be functionally modified or destined for...

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Bibliographic Details
Main Authors: Unni Grimholt, Hilde Sindre, Arvind Y. M. Sundaram
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1554680/full
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