Colistine pharmacokinetics and Colistimethate sodium daily dose calculation in children with chemotherapy induced neutropenia

A standard fractional Colistimethate sodium dosing regimen does not allow in most cases reach the target values of AUC / MIC index, determining the Colistine pharmacological efficacy. Use of the proposed algorithm for daily dose calculating increases the incidence to achieve Colistine concentration...

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Bibliographic Details
Main Authors: V. I. Zakharevich, V. V. Dmitriev
Format: Article
Language:Russian
Published: ABV-press 2014-09-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/115
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