SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer

SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer

Abstract Background Bladder cancer (BC) is one of the most common malignancies worldwide. G protein-coupled receptors (GPCRs) are a large family of transmembrane proteins that are increasingly recognised as key players in cancer biology, affecting cell signalling and the tumour microenvironment. The...

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Bibliographic Details
Main Authors: Jingming Zhuang, Yang Wang, Xinyong Wu, Zijing Peng, Zhengnan Huang, Chao Zhao, Bing Shen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
G protein coupled receptor
Bladder cancer
Tumour microenvironment
SIGMAR1
ER stress
Online Access:https://doi.org/10.1186/s12967-025-06393-7
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https://doi.org/10.1186/s12967-025-06393-7

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