Exploring cotton plant compounds for novel treatments against brain-eating Naegleria fowleri: An In-silico approach.

To find potential inhibitors of Naegleria fowleri S-adenosyl-L-homocysteine hydrolase (NfSAHH), a brain-eating parasite, structure-based drug design was adopted. N. fowlerica causes primary amebic meningoencephalitis (PAM), a fatal central nervous system (CNS) disorder if untreated. NfSAHH protein (...

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Main Authors: Aqal Zaman, Sana Noor, Iqra Ahmad, Muhammad Shehroz, Nour Alhajri, Sibtain Ahmed, Umar Nishan, Sheheryar Sheheryar, Riaz Ullah, Abdelaaty A Shahat, Hanna Dib, Mohibullah Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319032
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