The size of CD8+ infiltrating T cells is a prognostic marker for esophageal squamous cell carcinoma

The size of CD8+ infiltrating T cells is a prognostic marker for esophageal squamous cell carcinoma

Abstract In many malignancies, an increased number of tumor-infiltrating lymphocytes (TILs) is recognized as a favorable prognostic factor, with exceptions such as renal cell carcinoma. However, the clinical significance of TIL size remains unclear. T-cell activation by mitogens increases cell size,...

Full description

Saved in:
Bibliographic Details
Main Authors: Kengo Shigehara, Noriko Kawai, Tomohide Shirosaki, Yuma Ebihara, Aiko Murai, Akari Takaya, Serina Tokita, Kenta Sasaki, Naoki Shijubou, Terufumi Kubo, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Yutaka Hatanaka, Tomoko Mitsuhashi, Toshiaki Shichinohe, Yoshihiko Hirohashi, Satoshi Hirano, Toshihiko Torigoe
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Esophageal squamous cell carcinoma
Tumor-infiltrating lymphocytes
CD8
Lymphocyte size
Online Access:https://doi.org/10.1038/s41598-025-10885-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-10885-3

Similar Items