Estradiol Downregulates MicroRNA-193a to Mediate Its Anti-Mitogenic Actions on Human Coronary Artery Smooth Muscle Cell Growth

Estradiol Downregulates MicroRNA-193a to Mediate Its Anti-Mitogenic Actions on Human Coronary Artery Smooth Muscle Cell Growth

The abnormal growth of smooth muscle cells (SMCs) contributes to the vascular remodeling associated with coronary artery disease, a leading cause of death in women. Estradiol (E2) mediates cardiovascular protective actions, in part, by inhibiting the abnormal growth (proliferation and migration) of...

Full description

Saved in:
Bibliographic Details
Main Authors: Lisa Rigassi, Marinella Rosselli, Brigitte Leeners, Mirel Adrian Popa, Raghvendra Krishna Dubey
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
estradiol
miRNA-139a
smooth muscle cells
proliferation
migration
cardiovascular disorders
Online Access:https://www.mdpi.com/2073-4409/14/15/1132
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/14/15/1132

Similar Items