Transcutaneous auricular vagus nerve stimulation to treat narcolepsy type 1 (TARGET-NT1): A two-arm, randomised, sham-controlled trial

Transcutaneous auricular vagus nerve stimulation to treat narcolepsy type 1 (TARGET-NT1): A two-arm, randomised, sham-controlled trial

To assess exploratorily the safety and efficacy of transcutaneous auricular vagus nerve stimulation (tVNS) as an adjunctive therapy in improving symptoms in patients with narcolepsy type 1 (NT1). The TARGET-NT1 trial, a two-arm, double-blinded, sham-controlled trial was conducted from April 2022, to...

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Main Authors: Yuanhang Pan, Yingchi Zhang, Ziliang Xu, Zihan Wei, Rui Pan, Gengyao Hu, Xiaoli Wang, Lei Yang, Dianwei Wu, Xinbo Zhang, Xinyu Wen, Shuyi Qu, Chenwei Li, Zhe Zhu, Yuwen Gao, Xiaodan Shi, Yuanqiang Zhu, Kejian Wu, Duolao Wang, Yonghong Liu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neurotherapeutics
Subjects:
Narcolepsy type 1
Transcutaneous auricular vagus nerve stimulation
Excessive daytime sleepiness
Randomized controlled trial
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747925000820
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