Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invasive pancreatic cancer

Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invasive pancreatic cancer

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and most patients are diagnosed at a stage where the disease is unresectable, locally advanced, or has already metastasized. Invasive pancreatic cancer is believed to arise through a progression of noninvasive ductal le...

Full description

Saved in:
Bibliographic Details
Main Authors: Fereshteh Rezagholizadeh, Adel Salimi, Ali Sharifi-Zarchi, Farid Azmoudeh-Ardalan, Kazem Mousavizadeh, Fatemeh Tajik, Mahshid Panahi, Hossein Khorramdelazad, Masoud Baghai Wadji, Atefeh Kashanizadeh, Alireza Lotfalizadeh, Seyed Javad Mowla, Mohammad Taghi Joghataei
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
RAD51AP1
Pancreatic cancer
Laser-captured microdissection
Pancreatic intraepithelial neoplasia
Metastasis
Biomarker
Online Access:https://doi.org/10.1186/s12935-025-03810-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12935-025-03810-1

Similar Items