Beyond gold: the chemoenhancing mechanism and therapeutic potential of auranofin in melanoma

Beyond gold: the chemoenhancing mechanism and therapeutic potential of auranofin in melanoma

Objective: The objective of the current study was to evaluate the chemosensitizing capacity of auranofin (AF), a gold (I) complex traditionally used in rheumatoid arthritis treatment, in potentiating the cytotoxic effects of doxorubicin (DOX) in melanoma cell models, specifically drug-sensitive (B16...

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Bibliographic Details
Main Authors: Xiaofeng Wang, Yingnan Liu, Wuqiong Zhang, Zhongda Li, Su Li, Jiaxin Chen, Qi Li, Xiaoman Suo, Yanqiao Zeng, Guofang Zhang, Yang Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2025-06-01
Series:Cancer Biology & Medicine
Subjects:
auranofin
trxr1
anti-cancer
drug resistance
molecular dynamics simulation
Online Access:https://www.cancerbiomed.org/content/22/6/672
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https://www.cancerbiomed.org/content/22/6/672

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