Identification of CD36 as a contributor in inflammatory response of rheumatoid arthritis and screening of feasible bioactive drugs targeting it

Identification of CD36 as a contributor in inflammatory response of rheumatoid arthritis and screening of feasible bioactive drugs targeting it

Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory disease. This study aims to identify candidate therapeutic targets and promising drugs for RA. Methods RA-related microarray datasets (GSE77298 and GSE206848) and inflammatory genes (IRGs) were downloaded from Gene Expression Om...

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Bibliographic Details
Main Authors: Dan Xuan, Xiaowan Wang, Dandan Feng, Li Wang, Yonghui Xia
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Hereditas
Subjects:
Rheumatoid arthritis
WGCNA
Virtual screening
CD36
Inflammatory response
Fibroblast-like synovial cells
Online Access:https://doi.org/10.1186/s41065-025-00450-3
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https://doi.org/10.1186/s41065-025-00450-3

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