Temperature- and pH-Responsive Poly(NIPAM-<i>co</i>-HEMA-<i>co</i>-AAm) Nanogel as a Smart Vehicle for Doxorubicin Delivery; Combating Colorectal Cancer

Temperature- and pH-Responsive Poly(NIPAM-<i>co</i>-HEMA-<i>co</i>-AAm) Nanogel as a Smart Vehicle for Doxorubicin Delivery; Combating Colorectal Cancer

In this project, a new class of temperature- and pH-sensitive hydrogel consisting of <i>N</i>-isopropyl acrylamide (NIPAM), hydroxyethyl methacrylate (HEMA), and acrylamide (AAm) was prepared via a controlled route through the reversible addition–fragmentation chain-transfer (RAFT) polym...

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Bibliographic Details
Main Authors: Soheila Ghasemi, Mehdi Najafi, Mohammad Doroudian, Banafsheh Rastegari, Abbas Behzad-Behbahani, Hadis Soltanimehr, Fatemeh Farjadian
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Gels
Subjects:
hydrogel
smart vehicle
RAFT polymerization
PNIPAM
doxorubicin
drug delivery
Online Access:https://www.mdpi.com/2310-2861/11/4/227
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