Heterogeneity of IL-15-expressing mesenchymal stromal cells controls natural killer cell development and immune cell homeostasis

Heterogeneity of IL-15-expressing mesenchymal stromal cells controls natural killer cell development and immune cell homeostasis

Abstract Bone marrow (BM) mesenchymal stromal cells (MSC) provide microenvironmental niches that support hematopoietic stem cells and regulate hematopoiesis. Whether functional heterogeneity among BM MSCs contributes to the development and survival of distinct immune cell lineages remains incomplete...

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Main Authors: Carmen Stecher, Romana Bischl, Anna Schmid-Böse, Stefanie Ferstl, Elisabeth Potzmann, Magdalena Frank, Nina Braun, Matthias Farlik, Richard A. Flavell, Dietmar Herndler-Brandstetter
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61231-0
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https://doi.org/10.1038/s41467-025-61231-0

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