In Vitro Efficacy and Toxicity Assessment of an Amphotericin B Gel for the Treatment of Cutaneous Leishmaniasis

In Vitro Efficacy and Toxicity Assessment of an Amphotericin B Gel for the Treatment of Cutaneous Leishmaniasis

<b>Background/Objectives</b>: Leishmaniasis is a neglected tropical disease caused by a protozoan parasite of <i>Leishmania</i>. This study aimed to evaluate the in vitro efficacy and toxicity of a previously developed amphotericin gel as a possible treatment for cutaneous le...

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Bibliographic Details
Main Authors: Lilian Sosa, Lupe Carolina Espinoza, Marcelle Silva-Abreu, Ximena Jaramillo-Fierro, Diana Berenguer, Cristina Riera, María Rincón, Ana C. Calpena
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
cutaneous leishmaniasis
amphotericin B
Pluronic<sup>®</sup> F127
topical delivery
permeation studies
in vitro cytotoxicity
Online Access:https://www.mdpi.com/1424-8247/18/3/427
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https://www.mdpi.com/1424-8247/18/3/427

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