Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy

Liquiritigenin (LIQ) is a dihydroflavonone monomer compound with a planar ring structure that exhibits potent anti-inflammatory activity. The post-translational modifications (PTMs) of histones are closely associated with inflammatory diseases. To explore the relationships between the anti-inflammat...

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Main Authors: Ping Liu, Jun Zhang, Jingdan Zhang, Yucheng Yuan, Zhiqing Liu, Sixian Chen, Kaifeng Chen, Li Dong, Zhiyuan Cheng, Yinan Zhang, Meiyu Geng, Minjia Tan, Wensi Zhao, Dong Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1566567/full
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