Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids

Abstract In addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs) have multiple other mechanisms that may contribute to clinical effects, and some of these latter actions prompt repurposing of SSRIs for non-psychiatric indications. In a recent study of the SSRIs...

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Bibliographic Details
Main Authors: Yukitoshi Izumi, Angela M. Reiersen, Eric J. Lenze, Steven J. Mennerick, Charles F. Zorumski
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03185-3
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