En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration
Purpose. “En face” is an emerging imaging technique derived from spectral domain optical coherence tomography (OCT). It produces frontal sections of retinal layers, also called “C-scan OCT.” Outer retinal tubulations (ORTs) in age-related macular degeneration (AMD) are a recent finding evidenced by...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2012/542417 |
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| author | Benjamin Wolff Alexandre Matet Vivien Vasseur José-Alain Sahel Martine Mauget-Faÿsse |
| author_facet | Benjamin Wolff Alexandre Matet Vivien Vasseur José-Alain Sahel Martine Mauget-Faÿsse |
| author_sort | Benjamin Wolff |
| collection | DOAJ |
| description | Purpose. “En face” is an emerging imaging technique derived from spectral domain optical coherence tomography (OCT). It produces frontal sections of retinal layers, also called “C-scan OCT.” Outer retinal tubulations (ORTs) in age-related macular degeneration (AMD) are a recent finding evidenced by spectral-domain OCT. The aim of this study is to characterize the morphology of ORT according to the form of AMD, using “en-face” spectral domain OCT. Methods. “En face” OCT imaging was prospectively performed in 26 consecutive eyes with AMD that also had ORT. Results. There were 15 neovascular, 8 atrophic, and 3 eyes with a mixed (fibrotic and atrophic) form of AMD. Among the neovascular group, the most frequent tubulation pattern on “en-face” OCT was a branching network emanating from a fibrovascular scar; we term this pattern as “pseudodendritic.” It did not require treatment when observed as an isolated finding. In all cases of atrophic AMD, the tubular network was located at the edge of the geographic atrophy area, and formed a “perilesional” pattern. Six atrophic cases showed tubular invaginations inside this area. Conclusion. “En face” OCT is a valuable technique in the diagnosis and followup of macular disease. It revealed the main characteristic patterns of ORT associated with neovascular and atrophic AMD. |
| format | Article |
| id | doaj-art-d3f9eafcb5074a10b98885525dccd4a0 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-d3f9eafcb5074a10b98885525dccd4a02025-02-03T01:09:38ZengWileyJournal of Ophthalmology2090-004X2090-00582012-01-01201210.1155/2012/542417542417En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular DegenerationBenjamin Wolff0Alexandre Matet1Vivien Vasseur2José-Alain Sahel3Martine Mauget-Faÿsse4Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceRothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceRothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceRothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceRothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FrancePurpose. “En face” is an emerging imaging technique derived from spectral domain optical coherence tomography (OCT). It produces frontal sections of retinal layers, also called “C-scan OCT.” Outer retinal tubulations (ORTs) in age-related macular degeneration (AMD) are a recent finding evidenced by spectral-domain OCT. The aim of this study is to characterize the morphology of ORT according to the form of AMD, using “en-face” spectral domain OCT. Methods. “En face” OCT imaging was prospectively performed in 26 consecutive eyes with AMD that also had ORT. Results. There were 15 neovascular, 8 atrophic, and 3 eyes with a mixed (fibrotic and atrophic) form of AMD. Among the neovascular group, the most frequent tubulation pattern on “en-face” OCT was a branching network emanating from a fibrovascular scar; we term this pattern as “pseudodendritic.” It did not require treatment when observed as an isolated finding. In all cases of atrophic AMD, the tubular network was located at the edge of the geographic atrophy area, and formed a “perilesional” pattern. Six atrophic cases showed tubular invaginations inside this area. Conclusion. “En face” OCT is a valuable technique in the diagnosis and followup of macular disease. It revealed the main characteristic patterns of ORT associated with neovascular and atrophic AMD.http://dx.doi.org/10.1155/2012/542417 |
| spellingShingle | Benjamin Wolff Alexandre Matet Vivien Vasseur José-Alain Sahel Martine Mauget-Faÿsse En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration Journal of Ophthalmology |
| title | En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration |
| title_full | En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration |
| title_fullStr | En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration |
| title_full_unstemmed | En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration |
| title_short | En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration |
| title_sort | en face oct imaging for the diagnosis of outer retinal tubulations in age related macular degeneration |
| url | http://dx.doi.org/10.1155/2012/542417 |
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