In vivo and in silico dynamics of the development of Metabolic Syndrome.

In vivo and in silico dynamics of the development of Metabolic Syndrome.

The Metabolic Syndrome (MetS) is a complex, multifactorial disorder that develops slowly over time presenting itself with large differences among MetS patients. We applied a systems biology approach to describe and predict the onset and progressive development of MetS, in a study that combined in vi...

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Main Authors: Yvonne J W Rozendaal, Yanan Wang, Yared Paalvast, Lauren L Tambyrajah, Zhuang Li, Ko Willems van Dijk, Patrick C N Rensen, Jan A Kuivenhoven, Albert K Groen, Peter A J Hilbers, Natal A W van Riel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Computational Biology
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pcbi.1006145/1/pcbi.1006145.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210222%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210222T130303Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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