A gelable polymer loaded with curcumin and apatinib absorbed in gelatin sponge delays postoperative residual tumor growth

A gelable polymer loaded with curcumin and apatinib absorbed in gelatin sponge delays postoperative residual tumor growth

Abstract Surgical resection of the tumor remains the preferred treatment for most solid tumors at an early stage, however, residual tumor cells after surgical resection poses a considerable obstacle in cancer treatment. Here, we developed a gel carrier using a cellulose-based gel-forming polymer (CT...

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Main Authors: Zhuo-Nan Meng, Jian-Yuan Chen, Chong Yu, Ai-hong Zheng, O. Sreekanth Reddy, Kai-Yan Liu, Yong-Rui Su, Shi-Tai Zhang, Yin-Shuang Wang, Hang-Yu Gu, Fu-Wei Wang, Song-Cheng Xu, Li-Tao Sun, Bing-Chen Chen, Wing-Fu Lai, Guo-Qing Wu, Da-Hong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Curcumin
Apatinib
Gelatin sponge
Gel-forming polymer
Postoperative residual tumor
Online Access:https://doi.org/10.1038/s41598-025-97732-7
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https://doi.org/10.1038/s41598-025-97732-7

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