Fc-optimized CD276 antibody enhances NK cell activation against non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is one of the most common and lethal cancers worldwide, with a poor prognosis for many patients, especially in advanced stages. The development of immune checkpoint inhibitors (ICIs) has transformed treatment strategies for NSCLC. ICIs targeting PD-1/PD-L1 have sho...

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Bibliographic Details
Main Authors: Sylwia A. Stefańczyk, Xenija Kaiser, Ilona Hagelstein, Samuel Holzmayer, Latifa Zekri, Susanne Jung, Melanie Märklin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1624751/full
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