Co-administration of coenzyme Q10 and curcumin mitigates cognitive deficits and exerts neuroprotective effects in aluminum chloride-induced Alzheimer's disease in aged mice

Co-administration of coenzyme Q10 and curcumin mitigates cognitive deficits and exerts neuroprotective effects in aluminum chloride-induced Alzheimer's disease in aged mice

Aluminum chloride (AlCl3), a known neurotoxic and Alzheimerogenic metal disrupts redox homeostasis which plays a pivotal role in pathophysiology of neurodegenerative disorders, particularly cognitive decline. The current study was designed to unveil the long-term neuroprotective outcomes and efficac...

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Bibliographic Details
Main Authors: Nida Rasheed, Hafiza Khushbakht Hussain, Zohabia Rehman, Azka Sabir, Waseem Ashraf, Tanveer Ahmad, Faleh Alqahtani, Imran Imran
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Experimental Gerontology
Subjects:
Ubiquinone
Curcumin
Memory loss
Geriatric mice
Oxidative stress
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S053155652400305X
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