Refractory nontuberculous mycobacterial infection and potential hidden immunodeficiency related to RAG mutation and production of anti-interferon-α autoantibodies: a case report

Refractory nontuberculous mycobacterial infection and potential hidden immunodeficiency related to RAG mutation and production of anti-interferon-α autoantibodies: a case report

Abstract Background Nontuberculous mycobacterial infectious diseases are associated with host immunological status. Neutralizing anti-interferon (IFN)-γ autoantibodies have been considered as a significant cause of nontuberculous mycobacterial infections. However, another autoantibody specifically t...

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Bibliographic Details
Main Authors: Xiaona Liang, Hanlin Liang, Siqiao Liang, Yan Ning, Zengtao Luo, Quanfang Chen, Zhiyi He
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Infectious Diseases
Subjects:
Nontuberculous mycobacterial infection
Anti-interferon-α autoantibody
Immunodeficiency
Recombinase activating gene
Online Access:https://doi.org/10.1186/s12879-025-10975-7
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https://doi.org/10.1186/s12879-025-10975-7

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