Modulation of atherogenesis biomarkers by PCSK9 inhibitors in Lp(a)-stimulated human coronary artery endothelial cells
Abstract Background Atherosclerosis is a complex inflammatory disease driven by endothelial dysfunction. However, most in vitro studies rely on lipopolysaccharide (LPS) or oxidized LDL (oxLDL) as stimulants, overlooking the pathogenic role of lipoprotein(a) [Lp(a)]. Lp(a) is an independent and genet...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-025-04892-5 |
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