Carnosic Acid Production from Sugarcane Syrup by Engineered Yeast in Fed-Batch Fermentation

Carnosic Acid Production from Sugarcane Syrup by Engineered Yeast in Fed-Batch Fermentation

Phenolic diterpene carnosic acid (CA) is widely used in the food, nutritional health, and cosmetic industries due to its antioxidative and antimicrobial properties. This work aimed to overproduce CA in <i>Saccharomyces cerevisiae</i> from sugarcane syrup in fed-batch 2 L bioreactor ferme...

Full description

Saved in:

Bibliographic Details
Main Authors:	Erdem Carsanba, Sara Fernandes, Felipe Beato, Luís Carlos Carvalho, Ana Pintado, Ana Lopes, Mónica Ribeiro, Tânia Leal, Manuela Pintado, Carla Oliveira
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Series:	Fermentation
Subjects:	carnosic acid engineered <i>Saccharomyces cerevisiae</i> sugarcane syrup fed-batch fermentation dynamic dissolved oxygen trigger
Online Access:	https://www.mdpi.com/2311-5637/11/3/147
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Influence of Genetic Algorithm Parameters on Their Performance for Parameter Identification of a Yeast Fed-batch Fermentation Process Model
by: Maria Angelova, et al.
Published: (2024-12-01)

Enhancing Biomass Production and Biodesulfurization Efficiency of <i>Rhodococcus qingshengii</i> IGTS8: Evaluation of Batch, Repeated Batch and Fed-Batch Cultivation Techniques
by: Konstantinos Dimos, et al.
Published: (2025-07-01)

Effects of batch and fed-batch cultures on biomass and exopolysaccharide production of Lachnum calyculiforme
by: YE Ming, et al.
Published: (2010-11-01)

Influence of Substrate Concentrations on the Performance of Fed-Batch and Perfusion Bioreactors: Insights from Mathematical Modelling
by: John J. Fitzpatrick, et al.
Published: (2025-05-01)

High-Titer L-lactic Acid Production by Fed-Batch Simultaneous Saccharification and Fermentation of Steam-Exploded Corn Stover
by: Liheng Deng, et al.
Published: (2025-01-01)

Chitosan-Based Nanocapsules as a Delivery System of Hydrophobic Carnosic Acid, A Model Neuroprotective Drug
by: Odrobińska-Baliś J, et al.
Published: (2024-12-01)

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity
by: R. Babu, et al.
Published: (2025-01-01)

Optimization of conditions for ethanol production from sugarcane molasses by fermentation with Saccharomyces cerevisiae cells immobilized on cotton gauze
by: HAN Peng, LV Jiangbo, CHEN Fake, WEI Lanlan, HUANG Jiekai, NIU Fuxing
Published: (2025-03-01)

Carnosic acid enhances cisplatin sensitivity and suppresses gastric cancer progression via the TP53/SLC7A11/ALOX12 axis
by: Li Zhou, et al.
Published: (2025-07-01)

The protective effect of carnosic acid on dextran sulfate sodium-induced colitis based on metabolomics and gut microbiota analysis
by: Changhui Du, et al.
Published: (2023-07-01)

System metabolic engineering modification of Saccharomyces cerevisiae to increase SAM production
by: Liangzhuang Tan, et al.
Published: (2025-03-01)

Nutritional, physicochemical, and chemical characterization of carbonated sugarcane juice
by: Usama Irshad, et al.
Published: (2024-12-01)

Process for removing polycyclic aomatic hydrocarbons from carnosic acid and its antioxidant
by: ZHAO Yifei, et al.
Published: (2024-11-01)

Comprehensive Analysis and Production of Powdered Starter Using <i>Saccharomyces cerevisiae</i> YM45
by: Su Jeong Lee, et al.
Published: (2025-04-01)

Effective semi-fed-batch saccharification with high lignocellulose loading using co-culture of Clostridium thermocellum and Thermobrachium celere strain A9
by: Sreyneang Nhim, et al.
Published: (2025-01-01)

Carnosic Acid Directly Targets STING C‐Terminal Tail to Improve STING‐Mediated Inflammatory Diseases
by: Wenqing Mu, et al.
Published: (2025-04-01)

The In Silico Optimization of a Fed-Batch Reactor Used for the Enzymatic Hydrolysis of Chicory Inulin to Fructose by Employing a Dynamic Approach
by: Daniela Gheorghe, et al.
Published: (2025-03-01)

Emir ve Kalecik Karası Üzümlerinden Fermantasyon Sırasında izole Edilen Bazı Mayaların Teknolojik Özellikleri
by: Canan Nurgel, et al.
Published: (2003-01-01)

Effects of a <i>Saccharomyces cerevisiae</i>-Derived Postbiotic in Adult Labrador Retrievers Undergoing Exercise and Transport Stress
by: Claire L. Timlin, et al.
Published: (2024-11-01)

Optimizing bioprocessing efficiency with OptFed: Dynamic nonlinear modeling improves product-to-biomass yield
by: Guido Schlögel, et al.
Published: (2024-12-01)

Exploring the Potential of <i>Torulaspora delbrueckii</i>, <i>Starmerella bacillaris</i>, and <i>Saccharomyces cerevisiae</i> as a Probiotic Starter for Craft Beer Production
by: Carmen-Rodica Vrînceanu, et al.
Published: (2025-05-01)

Effects of Various Inocula Combinations of <i>Leuconostoc mesenteroides</i>, <i>Papiliotrema terrestris</i>, and <i>Saccharomyces cerevisiae</i> on Dough Fermentation and Final Bread Characteristics
by: Enrico Viola, et al.
Published: (2024-12-01)

CRISPRa-Mediated Triple-Gene Activation of <i>ARO10</i>, <i>ARO80,</i> and <i>ADH2</i> for Enhancing 2-Phenylethanol Biosynthesis via the Ehrlich Pathway in <i>Saccharomyces cerevisiae</i>
by: Zijing Zhu, et al.
Published: (2025-06-01)

Deciphering the Molecular Adapting Mechanism of Lactic Acid-Tolerant <i>Saccharomyces cerevisiae</i> Through Genomic and Transcriptomic Analysis
by: Haowei Fan, et al.
Published: (2025-06-01)

A Novel PCR-Based Tool to Trace Oenological <i>Saccharomyces cerevisiae</i> Yeast by Monitoring Strain-Specific Nucleotide Polymorphisms
by: Anna Baldisseri, et al.
Published: (2025-07-01)

Transcriptomic Identification of Core Regulatory Genes for Higher Alcohol Production in <i>Saccharomyces cerevisiae</i> at Different Sugar Concentrations in Wine Fermentation
by: Lu Chen, et al.
Published: (2025-04-01)

The Application of Multiple Strategies to Enhance Methylparaben Synthesis Using the Engineered <i>Saccharomyces cerevisiae</i>
by: Lu Liu, et al.
Published: (2025-04-01)

Comparative Proteomics of Two Flor Yeasts in Sparkling Wine Fermentation: First Approach
by: Juan C. García-García, et al.
Published: (2025-01-01)

Ultrasound-Assisted Kinetics of Alcoholic Fermentation at Varying Power Levels for the Production of Isaño Wine (<i>Tropaeolum tuberosum</i>)
by: Alejandro Coloma, et al.
Published: (2025-05-01)

Shedding Light on Calcium Dynamics in the Budding Yeast: A Review on Calcium Monitoring with Recombinant Aequorin
by: Larisa Ioana Gogianu, et al.
Published: (2024-11-01)

Formulation of a Functional Probiotic Beverage Using Maesil (<i>Prunus mume</i>) Syrup By-Product Fermented by <i>Lactiplantibacillus plantarum</i> KFOM 0042
by: Chan-Il Bae, et al.
Published: (2025-06-01)

Oenological Capabilities of Yeasts Isolated from High-Sugar Matrices (Manna and Honey) as Potential Starters and Co-Starters for Winemaking
by: Valentina Craparo, et al.
Published: (2024-06-01)

Cinética de produção de levedura seca em leito de jorro Production kinetics of dry yeast in spouted bed
by: Ana P. T. Rocha, et al.
Published: (2008-02-01)

diAcCA, a Pro-Drug for Carnosic Acid That Activates the Nrf2 Transcriptional Pathway, Shows Efficacy in the 5xFAD Transgenic Mouse Model of Alzheimer’s Disease
by: Piu Banerjee, et al.
Published: (2025-02-01)

Effect of Selective Substrates on Germination of Pomegranate (<i>Punica granatum</i>) and Trifoliate Orange (<i>Poncirus trifoliata</i>) Seeds with and Without the Presence of Plant-Beneficial Microorganisms
by: Helen Kalorizou, et al.
Published: (2025-03-01)

Is maple syrup the next sweetener substitute? Comparing the potential opportunities and challenges of maple syrup to other common sweeteners
by: Ihsan Shawki Akili, et al.
Published: (2025-03-01)

Impact of Co-Inoculation Patterns of <i>Wickerhamomyces anomalus</i> and <i>Saccharomyces cerevisiae</i> on Cider Quality and Aromatic Profiles
by: Yue Wei, et al.
Published: (2025-04-01)

Metabolic Influence of <i>S. boulardii</i> and <i>S. cerevisiae</i> in Cross-Kingdom Models of <i>S. mutans</i> and <i>C. albicans</i>
by: Ting Li, et al.
Published: (2025-04-01)

Wine Yeast Strains Under Ethanol-Induced Stress: Morphological and Physiological Responses
by: Elisa Aiello, et al.
Published: (2024-12-01)

<i>Saccharomyces cerevisiae</i>’s Response to Dysprosium Exposure
by: Masao Kishida, et al.
Published: (2025-04-01)