Pharmacokinetic Study and Tissue Distribution of Lorlatinib in Mouse Serum and Tissue Samples by Liquid Chromatography-Mass Spectrometry

In the present study, we developed and validated a rapid and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of lorlatinib in mouse serum and tissue samples, and such a method was successfully applied to investigate the pharmacokinetic study and tissue d...

Full description

Saved in:
Bibliographic Details
Main Authors: Wei Chen, Yafei Shi, Shuya Qi, Haiyan Zhou, Chunyu Li, Dujia Jin, Guohui Li
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2019/7574369
Tags: Add Tag
No Tags, Be the first to tag this record!