Integration of single cell and bulk transcriptomes identifies T cell stress subtypes in LUAD

Integration of single cell and bulk transcriptomes identifies T cell stress subtypes in LUAD

Abstract Background The unique stress response state of T cells (Tstr) is found in various cancers and correlates with altered Lung Adenocarcinoma (LUAD) tumor microenvironment and immunotherapy outcomes. However, fewer studies have been described on the relationship between Tstr and LUAD, and its m...

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Bibliographic Details
Main Authors: Shengping Min, Linfeng Pan, Xinyu Zhang, Huili Chen, Lixuan Qiu, Xinyu Wang, Yiluo Xie, Kai Zhang, Qiang Zhang, Chaoqun Lian, Jing Zhang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Lung adenocarcinoma
Tstr
Predictive model
Online Access:https://doi.org/10.1007/s12672-025-03170-2
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https://doi.org/10.1007/s12672-025-03170-2

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