Determination of T cell response against XBB variants in adults who received either monovalent wild-type inactivated whole virus or mRNA vaccine or bivalent WT/BA.4-5 COVID-19 mRNA vaccine as the additional booster

Determination of T cell response against XBB variants in adults who received either monovalent wild-type inactivated whole virus or mRNA vaccine or bivalent WT/BA.4-5 COVID-19 mRNA vaccine as the additional booster

Objectives: As the SARS-CoV-2 virus evolves more rapidly than vaccines are updated, T cell immunity potentially confers protection against disease progression and death from new variants. In this study, we aimed to assess whether the current boosting vaccination schemes offer sufficient T cell prote...

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Main Authors: Yun Sang Tang, Chee Wah Tan, Ka Chun Chong, Chunke Chen, Yuanxin Sun, Karen Yiu, Kwun Cheung Ling, Ken K.P. Chan, Malik Peiris, Chris Ka Pun Mok, David S. Hui
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Infectious Diseases
Subjects:
COVID-19
Vaccine
Cross-reactive
T cell response
Bivalent vaccine
XBB
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224003424
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