Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis
Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder with no effective treatment. Advances in neuroscience and systems biomedicine now enable the use of complex patient-specific in vitro disease models and cutting-edge computational tools for data integration, enhancing our...
Saved in:
| Main Authors: | Alise Zagare, Irina Balaur, Adrien Rougny, Claudia Saraiva, Matthieu Gobin, Anna S. Monzel, Soumyabrata Ghosh, Venkata P. Satagopam, Jens C. Schwamborn |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
|
| Series: | npj Parkinson's Disease |
| Online Access: | https://doi.org/10.1038/s41531-025-00914-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
FAIR assessment of Disease Maps fosters open science and scientific crowdsourcing in systems biomedicine
by: Irina Balaur, et al.
Published: (2025-05-01) -
MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss
by: Alise Zagare, et al.
Published: (2025-04-01) -
A guide for developing comprehensive systems biology maps of disease mechanisms: planning, construction and maintenance
by: Alexander Mazein, et al.
Published: (2023-06-01) -
Dysregulated Coagulation in Parkinson’s Disease
by: Xinqing Wang, et al.
Published: (2024-11-01) -
Protocol to identify regulatory modules in Parkinson’s disease progression using miRNA data and Boolean modeling
by: Ahmed Abdelmonem Hemedan, et al.
Published: (2025-06-01)