Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder with no effective treatment. Advances in neuroscience and systems biomedicine now enable the use of complex patient-specific in vitro disease models and cutting-edge computational tools for data integration, enhancing our...

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Bibliographic Details
Main Authors: Alise Zagare, Irina Balaur, Adrien Rougny, Claudia Saraiva, Matthieu Gobin, Anna S. Monzel, Soumyabrata Ghosh, Venkata P. Satagopam, Jens C. Schwamborn
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00914-3
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