Calcium nanoparticles target and activate T cells to enhance anti-tumor function

Calcium nanoparticles target and activate T cells to enhance anti-tumor function

Abstract Calcium signaling plays a crucial role in the activation of T lymphocytes. However, modulating calcium levels to control T cell activation in vivo remains a challenge. In this study, we investigate T cell activation using 12-myristate 13-acetate (PMA)-encapsulated CaCO3 nanoparticles. We fi...

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Main Authors: Wei Yang, Zhizi Feng, Xinning Lai, Jianwen Li, Zhengwei Cao, Fangchao Jiang, Fanghui Chen, Shuyue Zhan, Feng Kong, Li Yang, Yong Teng, Wendy T. Watford, Gang Zhou, Jin Xie
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54402-y
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https://doi.org/10.1038/s41467-024-54402-y

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