Recruitment of the cellular lipid transport protein CERT to C. psittaci inclusions regulates the timing of bacterial egress

Recruitment of the cellular lipid transport protein CERT to C. psittaci inclusions regulates the timing of bacterial egress

Abstract Egress of intracellular pathogens is highly regulated and carefully timed. For the zoonotic bacterium C. psittaci, the predominant egress pathway is Chlamydia-containing sphere (CCS) formation, a calcium-dependent sequential mechanism including protease activity, inclusion membrane destabil...

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Bibliographic Details
Main Authors: Jana Scholz, Gudrun Holland, Michael Laue, Sebastian Banhart, Dagmar Heuer
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Chlamydia psittaci
Chlamydia
Egress
Obligate intracellular pathogens
Membrane contact sites
CERT
Online Access:https://doi.org/10.1038/s41598-025-02077-w
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https://doi.org/10.1038/s41598-025-02077-w

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