mTORC2 is crucial for regulating the recombinant Mycobacterium tuberculosis CFP-10 protein-induced phagocytosis in macrophages

mTORC2 is crucial for regulating the recombinant Mycobacterium tuberculosis CFP-10 protein-induced phagocytosis in macrophages

Abstract Mycobacterium tuberculosis (M. tuberculosis, Mtb) is a pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of most cases of tuberculosis. Macrophages play essential roles in defense against invading pathogens, including M. tuberculosis. The study of M. tuberc...

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Main Authors: Xian-Hui Huang, Yu Wang, Liu-Ying Wu, Ye-Lin Jiang, Ling-Jie Ma, Xiao-Feng Shi, Xing Wang, Meng-Meng Zheng, Lu Tang, Yong-Liang Lou, Dan-Li Xie
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Immunology
Subjects:
Mycobacterium tuberculosis
Culture filtrate protein 10
Mammalian target of Rapamycin complex 2
Phagocytosis
Online Access:https://doi.org/10.1186/s12865-025-00715-6
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https://doi.org/10.1186/s12865-025-00715-6

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