consHLA: a next generation sequencing consensus-based HLA typing workflow

Abstract Background Human Leukocyte Antigens (HLA) play central roles in histocompatibility and immune system functions, including antigen presentation. Accurate typing of Class I and II HLA genes is crucial for transplant tissue matching, characterising autoimmune diseases and informing cancer immu...

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Bibliographic Details
Main Authors: Rachel Bowen-James, Weilin Wu, Marie Wong-Erasmus, Julian M. W. Quinn, Chelsea Mayoh, Mark J. Cowley
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Bioinformatics
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Online Access:https://doi.org/10.1186/s12859-025-06223-z
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