A protein vaccine of RBD integrated with immune evasion mutation shows broad protection against SARS-CoV-2

A protein vaccine of RBD integrated with immune evasion mutation shows broad protection against SARS-CoV-2

Abstract Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to emerge and evade immunity, resulting in breakthrough infections in vaccinated populations. There is an urgent need for the development of vaccines with broad protective effects. In this study, we selected h...

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Main Authors: Ran An, Hao Yang, Cong Tang, Qianqian Li, Qing Huang, Haixuan Wang, Junbin Wang, Yanan Zhou, Yun Yang, Hongyu Chen, Wenhai Yu, Bai Li, Daoju Wu, Yong Zhang, Fangyu Luo, Wenqi Quan, Jingwen Xu, Dongdong Lin, Xiaoming Liang, Yuhuan Yan, Longhai Yuan, Xuena Du, Yuxia Yuan, Yanwen Li, Qiangming Sun, Youchun Wang, Shuaiyao Lu
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-02007-8
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https://doi.org/10.1038/s41392-024-02007-8

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