Targeted imaging of pulmonary fibrosis by a cyclic peptide LyP-1

Targeted imaging of pulmonary fibrosis by a cyclic peptide LyP-1

Abstract Pulmonary fibrosis (PF) is an interstitial chronic lung disease characterized by interstitial inflammation and extracellular matrix deposition, resulting in progressive lung dysfunction and ultimate respiratory failure. However, lacking of precise and noninvasive tracers for fibrotic lesion...

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Main Authors: Jing Li, Rui Shu, Tian Peng, Zifeng Yang, Mingzi Yang, Fengjiao Hu, Zhangqian Tao, Ying Hong, Zhiwei Cai, Jing Jia, Lu Wan, Song Tian, Zhi-Gang She, Hongliang Li, Xiao-Jing Zhang, Ejuan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Pulmonary fibrosis
LyP-1
Positron emission tomography
Tracer
Peptide
Non-invasive imaging
Online Access:https://doi.org/10.1038/s41598-024-78068-0
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https://doi.org/10.1038/s41598-024-78068-0

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