Anwendung der selektiven Amidspaltung zur Racematspaltung von Aminosäuren

A selective amide cleavage of dipeptide derivatives has been used for the resolution of N-acetylated α,α-disubstituted amino acids 3, prepared via the routes in Scheme 2. Condensation of the racemic amino acids with (S)-Phe-N(CH3)2 gave the diastereomeric dipeptides 10 and 10’ (Scheme 3), which wer...

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Bibliographic Details
Main Authors: Friedrich Stierli, Daniel Obrecht, Heinz Heimgartner
Format: Article
Language:deu
Published: Swiss Chemical Society 1984-12-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9632
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