CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway

CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway

Abstract Background Increasing evidence suggests that resistance to 5-fluorouracil (5FU) and oxaliplatin (OXP) in colorectal cancer (CRC) is linked to poor prognosis. This study aimed to probe the effect of colony-stimulating factor 2 (CSF2) on the resistance of CRC to 5FU and OXP. Methods The expre...

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Bibliographic Details
Main Authors: Hairong Zhou, Zhenyuan Gao, Xiao Wu, Yaping Wang, Lu Zhang
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Colorectal cancer
Resistance
CSF2
Notch pathway
Online Access:https://doi.org/10.1007/s12672-025-02285-w
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https://doi.org/10.1007/s12672-025-02285-w

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