Time cell sequences during delay intervals are not dependent on brain state and do not support hippocampus-dependent working memory

Abstract Working memory (WM) is essential for performing cognitive tasks, and sequentially active hippocampal cells over many seconds (‘time cells’) have been observed during WM retention. Time cells predominantly occur when neural activity oscillates at theta frequency. To examine whether time cell...

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Bibliographic Details
Main Authors: Li Yuan, Jose F. Figueroa, Ameen Khan, Gautam Narayan, Jill K. Leutgeb, Stefan Leutgeb
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62498-z
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