Immune, metabolic, anatomical, and functional features of people after successful tuberculosis treatment: an exploratory analysis

Abstract We explored the underlying mechanisms that may drive post-tuberculosis (TB) lung disease, a multifactorial, heterogenous, and prevalent disease. Extensive clinical phenotyping through fluorine-18 Fluorodeoxyglucose (FDG) positron emission tomography (PET)-computed tomography (CT) scans, pul...

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Main Authors: Tariq Webber, Candice Macdonald, Michele Tameris, Nicolette Tredoux, Anandi Bierman, Andrea Gutschmidt, Susanne Tönsing, Andriëtte Hiemstra, Firdows Noor, Candice Snyders, Tracy Richardson, Bernadine Fransman, Brian Allwood, Mark Hatherill, Leanie Kleynhans, André G. Loxton, Gerhard Walzl, Novel Chegou, Nelita du Plessis, Jane A Shaw, Stephanus T. Malherbe
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01656-1
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