Mimicking women’s endocrine milieu in mice for women’s health-related studies
Abstract To improve preclinical studies and their translation, patient-derived xenografts (PDXs) are increasingly used. They have human-specific tumor characteristics and reflect intra and inter-tumor heterogeneity. However, the endocrine milieu differs between humans and host mice. In light of sex-...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
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| Series: | npj Women's Health |
| Online Access: | https://doi.org/10.1038/s44294-025-00060-4 |
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