Effects of low-intensity pulsed ultrasound on clinical parameters in atherosclerotic peripheral artery disease patients with chronic limb-threatening ischemia

Effects of low-intensity pulsed ultrasound on clinical parameters in atherosclerotic peripheral artery disease patients with chronic limb-threatening ischemia

Abstract Chronic limb-threatening ischemia (CLTI) is a major public health problem. Low-intensity pulsed ultrasound (LIPUS) has been shown to improve ischemic limb conditions in patients with CLTI. However, the possible mechanisms of these benefits require further understanding. A total of 37 athero...

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Main Authors: Masato Kajikawa, Farina Mohamad Yusoff, Takayuki Yamaji, Tatsuya Maruhashi, Shinji Kishimoto, Takahiro Harada, Aya Mizobuchi, Shunsuke Tanigawa, Yukiko Nakano, Kazuaki Chayama, Chikara Goto, Ayumu Nakashima, Yukihito Higashi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Chronic limb-threatening ischemia
Atherosclerosis
Endothelial function
Angiogenesis
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-95145-0
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https://doi.org/10.1038/s41598-025-95145-0

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